The European Medical Agency (EMA) has issued a draft guideline on the quality and equivalence of topical products.The equivalence for complex semisolid formulations involves several steps: the same quantitative content, the same microstructure, the same release, and permeation profile.In this paper, several batches of a insulatd food jar low streng
Background Aurora kinases play an essential role in the orchestration of chromosome separation and cytokinesis during mitosis.Small-molecule inhibition of the aurora kinases has been shown to result in inhibition of cell division, phosphorylation of histone H3 and the induction of apoptosis Puzzles + Games in a number of cell systems.These characte
Lei Sheng,1,* Wei Cao,2,* Pingping Lin,3 Weili Chen,1 Hongrong Xu,1 Chunjiu Zhong,4 Fei Yuan,1 Hanjing Chen,1 Hui Li,1 Chao Liu,1 Mengjie Yang,1 Xuening Li1 1Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; Bolleke 2Shanghai Rixin Biotechnology Co., Ltd, Shanghai, 200237,
Surface sediments are important systems for the removal of anthropogenically derived inorganic nitrogen in estuaries.They are often characterized Slippers by the presence of a microphytobenthos (MPB) biofilm, which can impact bacterial communities in underlying sediments for example by secretion of extracellular polymeric substances (EPS) and compe